Places to stay in Florence, South Carolina

We currently have 60 accommodations in and around Florence. There are also other regional listings available for Hotels, Inns, RV parks and other properties. You can filter these listings by the available types.

Visitors to our area of South Carolina will find the community of Florence alive with culture & entertainment for your family. Local restaurants include Jazz On Dargan, Local Motive Brewery, Town Hall, and El Agave Mexican Restaurant.

If you are travelling in the area, Florence is located close to Clock Branch School, Mount Zion African Methodist Episcopal Church, Florence Police Department, West Florence Rural Fire Department South Cashua Road Station and Warr Cemetery.

Booking.com

Selected and best reviewed properties in Florence

Hotel

The Country Inn & Suites

8 OUT OF 10 The staff at the hotel was wonderful. I actually have never had friendlier service anywhere. The hotel was pretty. The pool was nice and adequate size. The home made cookies were wonderful. Breakfast was included and it was great too. The rooms were comfortable and nice size. I would definitely .....
Hotel

The Sleep Inn

9 OUT OF 10 We travel through Florence every year. This is the nicest place we have stayed in area. Friendly service is what we really look for and Sleep Inn came through for us. We had a nice stay. Carpets should be cleaned more often is our only complaint but the room was clean and nice overall. They also .....
Hotel

The Comfort Suites

Our Comfort Suites® Florence I-95 hotel offers a new, modern feel alongside classic amenities for both leisure and business travelers. You'll find us just 15 minutes from the Florence Regional Airport and a short distance from some of the city's top attractions. Enjoy guest rooms that are 25% .....

Extended Stay / Suite

The Residence Inn

The award winning Residence Inn Marriott in Florence, SC features 94 spacious guest suites that are 50% larger than a standard hotel room. Each suite features flat panel LCD TVs with 45 HD channels, fully functional kitchens, three manager socials per week, an outdoor pool and hot tub, putting .....

Hotel

The Holiday Inn Express

Experience Top-Rated Service at Our Florence, SC Hotel Centrally located between Florida and New York in the heart of Florence, South Carolina, this hotel is at the intersection of I-95 and I-20 near the Florence Civic Center. The Holiday Inn Express hotel in Florence is just a short drive from .....

Hotel

The Travelodge

An excellent stopping point between Florida and New York, our hotel is conveniently located on I-95 exit 157, just 6 miles South of the I-20 Intersection. Popular area attractions including Darlington Raceway (12 miles), Freedom Florence Softball Complex (8 miles), Magnolia Mall (3 miles) and .....

Hotel

The Travel House Inn

The Travel House Inn is a beautiful property located on 7 acres of spacious, landscaped grounds. There are over 16 restaurants located right at our exit including Cracker Barrel and Ruby Tuesday. We are only 5 minutes away from the Civic Center and Sports Fields. There are over 18 challenging .....

Hotel

The Red Roof Inn

Florence, SC is one of the best non-smoking budget hotels in Florence, SC near the Florence Center. We are also close to the Florence Regional Airport, the Florence County Museum, Magnolia Mall, and Darlington Raceway. We offer our guests free WiFi, a seasonal outdoor pool, a free expanded cable .....

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Renamed properties