Hotels, Motels, Inns, B&B's, Resorts And Extended Stay in Sikeston, Missouri

Located 2 miles from the center of Sikeston. Whether you’re traveling for business or a vacationing tourist, alone or with your kids, you'll find everything you need to keep you on top of your game during your stay at our pet-friendly Comfort Inn & Suites® Sikeston hotel.

Located 2 miles from the center of Sikeston. Settle in for a relaxing stay at the Sikeston's newest hotel. Our Hampton Inn Sikeston hotel is located off Highway 60 and Interstate 55 just minutes from historic downtown and within walking distance to many shops and restaurants. Settle in .....

Located 3 miles from the center of Sikeston. Your Best Western Plus Sikeston is pet-friendly, welcoming the entire family whether it’s for a vacation or business trip. Hotels in Sikeston are renowned for hospitality, but the bar is set high at this property.

Located 2 miles from the center of Sikeston. The Pear Tree Inn Sikeston is conveniently located off I-55 in Sikeston near shopping and dining at local legend Lambert’s Café. Sikeston is halfway between St. Louis and Memphis in the Missouri Bootheel, bordering Kentucky and Arkansas.

Located 2 miles from the center of Sikeston. Large illuminating lights and contemporary decor welcome you to the Holiday Inn Express & Suites Sikeston. Our hotels address in Sikeston, MO surrounds you with fun and nearby attractions.