Hotels, Motels, Inns, B&B's, Resorts And Extended Stay in Sikeston, Missouri

There are 11 properties listed under Hotels, Motels and Extended Stay Suites in Sikeston available. All distances are from the center of Sikeston, so actual travel times may vary.


Hotel
★★★★
"Overall good place to stay overnight. I would not stay more then one night here. Nice location and street appearance."
1330 South Main Street
Sikeston, Missouri
Photograph of Holiday Inn Express, Sikeston
Listing updated 2024
Located 2 miles from the center of Sikeston. Large illuminating lights and contemporary decor welcome you to the Holiday Inn Express & Suites Sikeston. Our hotels address in Sikeston, MO surrounds you with fun and nearby attractions.
115 Hospitality Drive
Sikeston, Missouri
Photograph of Hampton Inn, Sikeston
Listing updated 2024
Hotel
Located 2 miles from the center of Sikeston. Expect a great stay at Hampton Inn Sikeston. Guests love our spacious rooms, free WiFi, free hot breakfast, heated indoor pool and fitness center..
1240 Commerce Drive
Sikeston, Missouri
Photograph of Pear Tree Inn Sikeston, Sikeston
Listing updated 2024
★★★
Located 2 miles from the center of Sikeston. The Pear Tree Inn Sikeston is conveniently located off I-55 in Sikeston near shopping and dining at local legend Lambert’s Café. Sikeston is halfway between St. Louis and Memphis in the Missouri Bootheel, bordering Kentucky and Arkansas.
2602 East Malone
Sikeston, Missouri
Photograph of Best Western Plus, Sikeston
Listing updated 2024
★★
Located 3 miles from the center of Sikeston. Your Best Western Plus Sikeston is pet-friendly, welcoming the entire family whether it’s for a vacation or business trip. Hotels in Sikeston are renowned for hospitality, but the bar is set high at this property.
120 South Interstate
Sikeston, Missouri
Photograph of Super 8, Sikeston
Listing updated 2024
Hotel
Located 2 miles from the center of Sikeston. Close to Miner Convention Center, shopping, and dining.
2609 East Malone
Sikeston, Missouri
Photograph of Comfort Inn, Sikeston
Listing updated 2024
Hotel
★★
Located 2 miles from the center of Sikeston. Whether you’re traveling for business or a vacationing tourist, alone or with your kids, you'll find everything you need to keep you on top of your game during your stay at our pet-friendly Comfort Inn & Suites® Sikeston hotel.
109 Matthews Lane
Sikeston, Missouri
Photograph of Days Inn & Suites by Wyndham Sikeston, Sikeston
Listing updated 2024
Located 3 miles from the center of Sikeston. All-suite hotel off I-55 and US-62, near Sikeston Jaycee Bootheel Rodeo.
220 South Interstate Drive
Sikeston, Missouri
Motel
110 South Interstate Drive
Sikeston, Missouri
833 East Malone
Sikeston, Missouri
100 Matthews Lane
Sikeston, Missouri

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