Places to stay in Jackson, Missouri

Jackson is a city in Cape Girardeau County, Missouri. It is the county seat of Cape Girardeau County. Jackson is named for U. S. President Andrew Jackson. It is a principal city of the Cape Girardeau–Jackson, MO-IL Metropolitan Statistical Area. Places to eat in the region include Mario's Pasta House, T-ravs, Delmonicos, and Steele Crest Winery & Brewery.

If you are travelling in the area, Jackson is located close to Iona School, Saint Francis Hospital Heliport, Upper Whitewater Creek, Old McKendree Chapel and Maple Grove School (historical).

The center of Jackson ( which is at is longitude -89°39'59.76 and latitude 37°22'56.28 ) is located and 8 miles away from Burfordville.

Available Jackson lodging

We currently have 8 accommodations in and around Jackson.

Jackson Hotels, Motels, Resorts, B&Bs and Extended Stay

Hotels

La Quinta Inn & Suites

Enjoy free breakfast, WiFi, and parking as well as a heated indoor pool and fitness center at La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau. Located off I-55 at Exit 99, 10 miles from Cape Girardeau Regional Airport (CGI), our .....
3003 South Old Orchard Road
Jackson, Missouri
Photograph of Comfort Suites, Jackson
Listing updated 2025
Hotels

Comfort Suites

Unwind in our Comfort Suites® Jackson-Cape Girardeau hotel. Our friendly staff is eager to welcome you with professional service and exceptional amenities designed to make your stay in Jackson a memorable one.
2904 Old Orchard Road
Jackson, Missouri
Hotels

Drury Inn & Suites

This Bavarian-style hotel off I-55 in Jackson may not look like the other Drury Inn & Suites on the outside, but our friendly staff always welcomes guests to relax in a clean, comfortable room and enjoy all of our free extras.
225 Drury Lane
Jackson, Missouri
Bed & Breakfasts

TLC Bed And Breakfast And Wellness Center

The B&B features four guest rooms, each with private bath and TV and a full breakfast. We are only minutes away from Cape Girardeau area attractions such as Southeast Missouri State University, Bollinger Mill and the Iron Montain and Southern Railroad.
203 Bellevue
Jackson, Missouri
Hotels

Town House Inn

517 East Jackson Boulevard
Jackson, Missouri

Jackson Camping & RV, Cottages, Rentals and Lodges / Ranches

Campsite / RV Parks

Cherokee Hills Campground

Nestled in dense forested land, Cherokee Hills Campground once held an encampment of Cherokee people who fled the Trail of Tears soon after their trecherous crossing of the Mississippi River in the harsh winter of 1838-39.
2112 County Road 607
Jackson, Missouri
Campsite / RV Parks

Trail of Tears State Park

The tragic history that gives Trail of Tears State Park its name provides a sharp contrast to the peaceful, serene setting and the abundance of recreational opportunities enjoyed by visitors today.
429 Moccasin Springs
Jackson, Missouri
Campsite / RV Parks

Silver Hills Guest Ranch

600 Peckew Trail
Jackson, Missouri
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Renamed properties